Mouse IL7 protein (Recombinant-Active) (No tag) (STJP011843)

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STJP011843-100
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Mouse IL7-No tag protein was developed from e. coli and has a target region of No tag. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <1 EU/Mu g of the protein by the LAL method.
Gene Symbol: Il7
Gene ID: 16196
Uniprot ID: IL7_MOUSE
Immunogen Region: Glu26-Ile154
Immunogen: Mus musculus (Mouse)
Function Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis. Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG. Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5.
Protein Name Interleukin-7
Il-7
Database Links Reactome: R-MMU-1266695
Cellular Localisation Secreted
Alternative Protein Names Interleukin-7 protein
Il-7 protein
Il7 protein
Il-7 protein

Information sourced from Uniprot.org

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