Mouse IL5 protein (Recombinant) (N-His) (STJP004687)

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STJP004687
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Short Description :Recombinant-Mouse IL5-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:Il5
Gene ID:16191
Uniprot ID:IL5_MOUSE
Immunogen:Mus musculus (Mouse)
Immunogen Region:Met21-Gly133
Function Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
Protein Name Interleukin-5
Il-5
B-Cell Growth Factor Ii
Bcgf-Ii
Cytotoxic T-Lymphocyte Inducer
Eosinophil Differentiation Factor
T-Cell Replacing Factor
Trf
Database Links Reactome: R-MMU-512988
Reactome: -MMU-5673001
Reactome: -MMU-912526
Cellular Localisation Secreted
Alternative Protein Names Interleukin-5 protein
Il-5 protein
B-Cell Growth Factor Ii protein
Bcgf-Ii protein
Cytotoxic T-Lymphocyte Inducer protein
Eosinophil Differentiation Factor protein
T-Cell Replacing Factor protein
Trf protein
Il5 protein
Il-5 protein

Information sourced from Uniprot.org

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