Mouse IL5 protein (Recombinant-Active) (C-His) (STJP011794)

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STJP011794-100
€691.88
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Mouse IL5-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: Il5
Gene ID: 16191
Uniprot ID: IL5_MOUSE
Immunogen Region: Met21-Gly133
Immunogen: Mus musculus (Mouse)
Function Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
Protein Name Interleukin-5
Il-5
B-Cell Growth Factor Ii
Bcgf-Ii
Cytotoxic T-Lymphocyte Inducer
Eosinophil Differentiation Factor
T-Cell Replacing Factor
Trf
Database Links Reactome: R-MMU-512988
Reactome: -MMU-5673001
Reactome: -MMU-912526
Cellular Localisation Secreted
Alternative Protein Names Interleukin-5 protein
Il-5 protein
B-Cell Growth Factor Ii protein
Bcgf-Ii protein
Cytotoxic T-Lymphocyte Inducer protein
Eosinophil Differentiation Factor protein
T-Cell Replacing Factor protein
Trf protein
Il5 protein
Il-5 protein

Information sourced from Uniprot.org

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