Mouse IL31RA protein (Recombinant) (N-His) (STJP009188)

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STJP009188
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse IL31RA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Il31ra
Gene ID: 218624
Uniprot ID: IL31R_MOUSE
Immunogen Region: Val19-Glu210
Immunogen: Mus musculus (Mouse)
Post Translational Modifications N-glycosylated.
Function Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.
Protein Name Interleukin-31 Receptor Subunit Alpha
Il-31 Receptor Subunit Alpha
Il-31r Subunit Alpha
Il-31r-Alpha
Il-31ra
Glm-R
Mglm-R
Gp130-Like Monocyte Receptor
Gp130-Like Receptor
Novel Cytokine Receptor 10
Nr10
Zcytor17
Database Links Reactome: R-MMU-6788467
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Presynaptic Cell Membrane
Cell Projection
Axon
Alternative Protein Names Interleukin-31 Receptor Subunit Alpha protein
Il-31 Receptor Subunit Alpha protein
Il-31r Subunit Alpha protein
Il-31r-Alpha protein
Il-31ra protein
Glm-R protein
Mglm-R protein
Gp130-Like Monocyte Receptor protein
Gp130-Like Receptor protein
Novel Cytokine Receptor 10 protein
Nr10 protein
Zcytor17 protein
Il31ra protein
Glmr protein

Information sourced from Uniprot.org

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