Mouse IL17C (Interleukin 17C) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016190)

Mouse IL17C (Interleukin 17C) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016190)

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STJE0016190
£442.50 - £604.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 12.2pg/mL
Detection Limit: 31.2-2000pg/mL
Short Description : This IL17C Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Il17c
Gene ID: 234836
Uniprot ID: IL17C_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Expressed by epithelial cells after bacterial challenge. Low expression, if any, in lymphocytes.
Post Translational Modifications
Function Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NFKB and MAPK pathways. Acts synergically with IL22, TNF and IL1B in inducing antibacterial peptides. May have protective function by maintaining epithelial homeostasis after an inflammatory challenge, such as that caused in the intestine by dextran sulfate sodium in a colitis model. May also promote an inflammatory phenotype, such as skin in a psoriasis model. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, such as autoimmune encephalitis.
Protein Name Interleukin-17c
Il-17c
Cytokine Cx2
Database Links
Cellular Localisation Secreted
Alternative ELISA Names Interleukin-17c ELISA kit
Il-17c ELISA kit
Cytokine Cx2 ELISA kit
Il17c ELISA kit
output

Information sourced from Uniprot.org

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