| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.126ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description: | This IL13Ra2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | Il13ra2 |
| Gene ID: | 16165 |
| Uniprot ID: | I13R2_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Cleaved by MMP8 leading to a soluble form that is also able to interact with IL13. |
| Function | Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-2 Il-13 Receptor Subunit Alpha-2 Il-13r Subunit Alpha-2 Il-13r-Alpha-2 Il-13ra2 Cd Antigen Cd213a2 |
| Database Links | Reactome: R-MMU-6785807 |
| Cellular Localisation | Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 2: Secreted |
| Alternative ELISA Names | Interleukin-13 Receptor Subunit Alpha-2 ELISA kit Il-13 Receptor Subunit Alpha-2 ELISA kit Il-13r Subunit Alpha-2 ELISA kit Il-13r-Alpha-2 ELISA kit Il-13ra2 ELISA kit Cd Antigen Cd213a2 ELISA kit Il13ra2 ELISA kit |
| output |
Information sourced from Uniprot.org
