| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse IL-13 alpha 1 receptor (IL13RA1)-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised 0.2 Mu m filtered PBS solution, pH7.2. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: | Il13ra1 |
| Gene ID: | 16164 |
| Uniprot ID: | I13R1_MOUSE |
| Immunogen Region: | ECD |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of mouse IL-13 receptor alpha 1 including a C terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Spleen, liver, thymus, heart, lung, kidney, testis, stomach, brain, skin, and colon.but not skeletal muscle. |
| Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-1 Il-13 Receptor Subunit Alpha-1 Il-13r Subunit Alpha-1 Il-13r-Alpha-1 Il-13ra1 Interleukin-13-Binding Protein Novel Cytokine Receptor 4 Nr4 Cd Antigen Cd213a1 |
| Database Links | Reactome: R-MMU-6785807 |
| Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-13 Receptor Subunit Alpha-1 protein Il-13 Receptor Subunit Alpha-1 protein Il-13r Subunit Alpha-1 protein Il-13r-Alpha-1 protein Il-13ra1 protein Interleukin-13-Binding Protein protein Novel Cytokine Receptor 4 protein Nr4 protein Cd Antigen Cd213a1 protein Il13ra1 protein Il13r protein Il13ra protein |
Information sourced from Uniprot.org