| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g of the protein by LAL method. |
| Immunogen Region: | Cys24-Glu189 |
| Immunogen: | Recombinant Mouse IFN-alpha 5 Protein is produced by HEK293 cells system. The target protein is expressed with sequence (Cys24-Glu189) of Mouse IFN-alpha 5 (Accession #NP_034635.2) fused with His tag at the C-Terminus. |
| Immunogen Sequence: | CDLPQTHNLRNKRALTLLVK MRRLSPLSCLKDRKDFGFPQ EKVGAQQIQEAQAIPVLSEL TQQVLNIFTSKDSSAAWNAT LLDSFCNEVHQQLNDLKACV MQQVGVQESPLTQEDSLLAV RKYFHRITVYLREKKHSPCA WEVVRAEVWRALSSSVNLLA RLSKEE |
| Background | IFN-alpha 5 belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
Information sourced from Uniprot.org
