Tissue Specificity | Expressed mainly in antigen-presenting immune cells, liver, kidney, brain, and placenta. Highly expressed in kidney, followed by epididymis and liver (at protein level). Detected in the tails of the spermatozoa in the testis and in the kidney tubules (at protein level). Constitutively expressed in brain. |
Post Translational Modifications | |
Function | Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Involved in immune regulation. |
Protein Name | Indoleamine 2 -3-Dioxygenase 2Ido-2Indoleamine 2 -3-Dioxygenase-Like Protein 1Indoleamine-Pyrrole 2 -3-Dioxygenase-Like Protein 1 |
Database Links | Reactome: R-MMU-71240 |
Cellular Localisation | |
Alternative ELISA Names | Indoleamine 2 -3-Dioxygenase 2 ELISA kitIdo-2 ELISA kitIndoleamine 2 -3-Dioxygenase-Like Protein 1 ELISA kitIndoleamine-Pyrrole 2 -3-Dioxygenase-Like Protein 1 ELISA kitIdo2 ELISA kitIndol1 ELISA kit |
output | |
Information sourced from Uniprot.org