Tissue Specificity | |
Post Translational Modifications | Phosphorylation at sites in the second and third cytoplasmic loops independently contribute to agonist-induced receptor down-regulation. |
Function | G-protein-coupled receptor for histamine, a biogenic amine that functions as an immune modulator and a neurotransmitter. Through the H1 receptor, histamine mediates the contraction of smooth muscles and increases capillary permeability due to contraction of terminal venules. Also mediates neurotransmission in the central nervous system and thereby regulates circadian rhythms, emotional and locomotor activities as well as cognitive functions. |
Protein Name | Histamine H1 ReceptorH1rHh1r |
Database Links | Reactome: R-MMU-390650Reactome: -MMU-416476 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Histamine H1 Receptor ELISA kitH1r ELISA kitHh1r ELISA kitHrh1 ELISA kitBphs ELISA kit |
output | |
Information sourced from Uniprot.org