Host: |
CHO cells |
Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Mouse GM-CSF-protein was developed from cho cells. For use in research applications. |
Conjugation: |
Unconjugated |
Formulation: |
Lyophilised from 0.2 Mu m filtered solution in PBS, pH 7.0. |
Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Immunoreactivity: |
The ED50 as determined by the dose-dependent stimulation of the proliferation of FDC-P1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. NA |
Gene Symbol: |
CSF2 |
Gene ID: |
1437 |
Uniprot ID: |
CSF2_HUMAN |
Immunogen Region: |
Mature chain |
Immunogen: |
Optimized DNA sequence encoding Mouse Granulocyte Macrophage-Colony Stimulating Factor mature chain was expressed in CHO Cells. NA |
Function | Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. |
Protein Name | Granulocyte-Macrophage Colony-Stimulating FactorGm-CsfColony-Stimulating FactorCsfMolgramostinSargramostim |
Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-6783783Reactome: R-HSA-8939246Reactome: R-HSA-912526 |
Cellular Localisation | Secreted |
Alternative Protein Names | Granulocyte-Macrophage Colony-Stimulating Factor proteinGm-Csf proteinColony-Stimulating Factor proteinCsf proteinMolgramostin proteinSargramostim proteinCSF2 proteinGMCSF protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance