Mouse GM-CSF protein (Recombinant) (STJP000224)
SPECIFICATIONS
HostCHO Cells
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding Mouse Granulocyte Macrophage-Colony Stimulating Factor mature chain was expressed in CHO Cells. NA
General Information
| Short Description | Recombinant-Mouse GM-CSF-protein was developed from cho cells. For use in research applications. |
| Host | CHO Cells |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered solution in PBS, pH 7.0. |
| Storage Instruction | Can be stored in working aliquots at 2ยฐC-8ยฐC C for one month, or at-20ยฐC C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/ยตg (1EU/ยตg). NA |
| Immunoreactivity | The ED50 as determined by the dose-dependent stimulation of the proliferation of FDC-P1 cells is โค 0.1 ng/ml, corresponding to a specific activity of โฅ 1 x 107 units/mg. NA |
Target Information
| Gene Symbol | CSF2 |
| Gene ID | 1437 |
| Uniprot ID | CSF2_HUMAN |
| Immunogen | Optimized DNA sequence encoding Mouse Granulocyte Macrophage-Colony Stimulating Factor mature chain was expressed in CHO Cells. NA |
| Immunogen Region | Mature chain |
Additional Info
| Function | Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. |
| Protein Name | Granulocyte-Macrophage Colony-Stimulating FactorGm-CsfColony-Stimulating FactorCsfMolgramostinSargramostim |
| Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-6783783Reactome: R-HSA-8939246Reactome: R-HSA-912526 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Granulocyte-Macrophage Colony-Stimulating Factor proteinGm-Csf proteinColony-Stimulating Factor proteinCsf proteinMolgramostin proteinSargramostim proteinCSF2 proteinGMCSF protein |
Information sourced from Uniprot.org