Tissue Specificity | Detected in pancreatic islets (at protein level). Detected in pancreatic islets and lungs. |
Post Translational Modifications | N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
Function | G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. |
Protein Name | Glucagon-Like Peptide 1 ReceptorGlp-1 ReceptorGlp-1-RGlp-1r |
Database Links | Reactome: R-MMU-381676Reactome: -MMU-418555Reactome: -MMU-420092 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Glucagon-Like Peptide 1 Receptor ELISA kitGlp-1 Receptor ELISA kitGlp-1-R ELISA kitGlp-1r ELISA kitGlp1r ELISA kit |
output | |
Information sourced from Uniprot.org