Tissue Specificity | Preferentially expressed in the liver and in testis. |
Post Translational Modifications | |
Function | FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. |
Protein Name | Fad-Linked Sulfhydryl Oxidase AlrAugmenter Of Liver Regeneration |
Database Links | |
Cellular Localisation | Mitochondrion Intermembrane SpaceMitochondrion |
Alternative ELISA Names | Fad-Linked Sulfhydryl Oxidase Alr ELISA kitAugmenter Of Liver Regeneration ELISA kitGfer ELISA kitAlr ELISA kitMNCb-0663 ELISA kit |
output | |
Information sourced from Uniprot.org