Tissue Specificity | |
Post Translational Modifications | Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. |
Function | Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. |
Protein Name | Growth Arrest-Specific Protein 6Gas-6Axl Receptor Tyrosine Kinase Ligand |
Database Links | Reactome: R-MMU-114608Reactome: -MMU-159763Reactome: -MMU-159782Reactome: -MMU-202733Reactome: -MMU-381426Reactome: -MMU-8957275 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Growth Arrest-Specific Protein 6 ELISA kitGas-6 ELISA kitAxl Receptor Tyrosine Kinase Ligand ELISA kitGas6 ELISA kit |
output | |
Information sourced from Uniprot.org