Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. |
Protein Name | Secreted Frizzled-Related Protein 3Sfrp-3FrezzledFritzFrizzled-Related Protein 1Frzb-1 |
Cellular Localisation | Secreted |
Alternative Protein Names | Secreted Frizzled-Related Protein 3 proteinSfrp-3 proteinFrezzled proteinFritz proteinFrizzled-Related Protein 1 proteinFrzb-1 proteinFrzb proteinFiz proteinFre proteinFrzb1 proteinSfrp3 protein |
Information sourced from Uniprot.org