| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Mouse FRZB-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | Frzb |
| Gene ID: | 20378 |
| Uniprot ID: | SFRP3_MOUSE |
| Immunogen Region: | Ala33-Ser323 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. |
| Protein Name | Secreted Frizzled-Related Protein 3Sfrp-3FrezzledFritzFrizzled-Related Protein 1Frzb-1 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Secreted Frizzled-Related Protein 3 proteinSfrp-3 proteinFrezzled proteinFritz proteinFrizzled-Related Protein 1 proteinFrzb-1 proteinFrzb proteinFiz proteinFre proteinFrzb1 proteinSfrp3 protein |
Information sourced from Uniprot.org