| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 34pg/mL |
| Detection Limit: | 78.1-5000pg/mL |
| Short Description : | This ErbB3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma or other biological fluids. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | Erbb3 |
| Gene ID: | 13867 |
| Uniprot ID: | ERBB3_MOUSE |
| Sample Type: | serum, plasma or other biological fluids. |
| Tissue Specificity | In the muscle, expression localizes to the synaptic sites of muscle fibers. |
| Post Translational Modifications | Autophosphorylated. Ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. |
| Function | Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it.ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. |
| Protein Name | Receptor Tyrosine-Protein Kinase Erbb-3Glial Growth Factor ReceptorProto-Oncogene-Like Protein C-Erbb-3 |
| Database Links | Reactome: R-MMU-1227986Reactome: -MMU-1236394Reactome: -MMU-1250196Reactome: -MMU-1257604Reactome: -MMU-1306955Reactome: -MMU-1358803Reactome: -MMU-1963642Reactome: -MMU-5673001Reactome: -MMU-6785631Reactome: -MMU-6811558Reactome: -MMU-8847993Reactome: -MMU-8863795 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Receptor Tyrosine-Protein Kinase Erbb-3 ELISA kitGlial Growth Factor Receptor ELISA kitProto-Oncogene-Like Protein C-Erbb-3 ELISA kitErbb3 ELISA kit |
| output |
Information sourced from Uniprot.org
