Mouse EGF protein (Recombinant) (His-Tag) (STJP019370)

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STJP019370
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Short Description :Recombinant-Mouse EGF-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Bioactivity
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 2mM DTT, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin:< 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity:Measured in a cell proliferation assay using mouse Balb/3T3 cell. The ED50 range ≤ 1ng/ml.
Gene Symbol:Egf
Gene ID:13645
Uniprot ID:EGF_MOUSE
Accession Number:NP_034243
Immunogen:Mouse
Immunogen Region:977-1029aa
Immunogen Sequence:NSYPGC PSSYDGYCLN GGVCMHIESL DSYTCNCVIG YSGDRCQTRD LRWWELR
Function EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
Protein Name Pro-Epidermal Growth Factor
Egf Cleaved Into - Epidermal Growth Factor
Database Links Reactome: R-MMU-114608
Reactome: -MMU-1227986
Reactome: -MMU-1236394
Reactome: -MMU-1250196
Reactome: -MMU-1257604
Reactome: -MMU-177929
Reactome: -MMU-179812
Reactome: -MMU-180292
Reactome: -MMU-180336
Reactome: -MMU-182971
Reactome: -MMU-1963642
Reactome: -MMU-212718
Reactome: -MMU-5673001
Reactome: -MMU-6785631
Reactome: -MMU-6811558
Reactome: -MMU-8847993
Reactome: -MMU-8856825
Reactome: -MMU-8856828
Reactome: -MMU-8863795
Reactome: -MMU-9009391
Reactome: -MMU-9013507
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Pro-Epidermal Growth Factor protein
Egf Cleaved Into - Epidermal Growth Factor protein
Egf protein

Information sourced from Uniprot.org