Mouse EFNA2 protein (Recombinant) (C-His) (STJP015568)
SPECIFICATIONS
HostMammalian Cells
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse EFNA2-C-His protein was developed from mammalian cells for the region C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | Efna2 |
| Gene ID | 13637 |
| Uniprot ID | EFNA2_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Ala20-Asn184 |
Additional Info
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis. |
| Protein Name | Ephrin-A2Cek7-LigandCek7-LElf-1Eph-Related Receptor Tyrosine Kinase Ligand 6Lerk-6 |
| Database Links | Reactome: R-MMU-2682334Reactome: -MMU-3928663Reactome: -MMU-3928665 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Ephrin-A2 proteinCek7-Ligand proteinCek7-L proteinElf-1 proteinEph-Related Receptor Tyrosine Kinase Ligand 6 proteinLerk-6 proteinEfna2 proteinElf1 proteinEpl6 proteinEplg6 proteinLerk6 protein |
Information sourced from Uniprot.org