Mouse DLL4 protein (Recombinant) (N-His) (STJP009933)

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STJP009933
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse DLL4-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Dll4
Gene ID: 54485
Uniprot ID: DLL4_MOUSE
Immunogen Region: Gly27-Ser177
Immunogen: Mus musculus (Mouse)
Function Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis.negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
Protein Name Delta-Like Protein 4
Drosophila Delta Homolog 4
Delta4
Database Links Reactome: R-MMU-9013507
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Delta-Like Protein 4 protein
Drosophila Delta Homolog 4 protein
Delta4 protein
Dll4 protein

Information sourced from Uniprot.org