Mouse DAND5 protein (Recombinant) (N-GST & C-His) (STJP009235)
SPECIFICATIONS
HostE.coli
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse DAND5-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | Dand5 |
| Gene ID | 23863 |
| Uniprot ID | DAND5_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Ser55-Leu185 |
Additional Info
| Function | Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development. Antagonist of BMP4 signaling. Antagonist of TGF-beta signaling. Independently of its role in left-right axis establishment, plays a role during heart development, possibly through the regulation of TGF-beta/Nodal signaling pathway. Displays anti-angiogenic activity by inhibiting endothelial sprouting, migration, and proliferation. Once internalized by endothelial cells, may alter their redox and glycolytic balance. |
| Protein Name | Dan Domain Family Member 5Cerberus-Like Protein 2Cerl-2 |
| Database Links | |
| Cellular Localisation | SecretedCirculating Dand5 May Be Uptaken By Endothelial Cells And Transported To Mitochondria |
| Alternative Protein Names | Dan Domain Family Member 5 proteinCerberus-Like Protein 2 proteinCerl-2 proteinDand5 proteinCerl2 proteinCoco proteinSp1 protein |
Information sourced from Uniprot.org