Mouse DAND5 protein (Recombinant) (N-GST & C-His) (STJP009235)

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STJP009235
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Short Description :Recombinant-Mouse DAND5-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:Dand5
Gene ID:23863
Uniprot ID:DAND5_MOUSE
Immunogen:Mus musculus (Mouse)
Immunogen Region:Ser55-Leu185
Function Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development. Antagonist of BMP4 signaling. Antagonist of TGF-beta signaling. Independently of its role in left-right axis establishment, plays a role during heart development, possibly through the regulation of TGF-beta/Nodal signaling pathway. Displays anti-angiogenic activity by inhibiting endothelial sprouting, migration, and proliferation. Once internalized by endothelial cells, may alter their redox and glycolytic balance.
Protein Name Dan Domain Family Member 5
Cerberus-Like Protein 2
Cerl-2
Database Links
Cellular Localisation Secreted
Circulating Dand5 May Be Uptaken By Endothelial Cells And Transported To Mitochondria
Alternative Protein Names Dan Domain Family Member 5 protein
Cerberus-Like Protein 2 protein
Cerl-2 protein
Dand5 protein
Cerl2 protein
Coco protein
Sp1 protein

Information sourced from Uniprot.org