| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 5.4pg/mL |
| Detection Limit: | 15.6-1000pg/mL |
| Short Description: | This CYR61 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | Ccn1 |
| Gene ID: | 16007 |
| Uniprot ID: | CCN1_MOUSE |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Low in kidney, adrenal gland, testes, brain, and ovary, moderate in heart, uterus, and skeletal muscle, highest in lung. |
| Post Translational Modifications | |
| Function | Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CCN1-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3. |
| Protein Name | Ccn Family Member 1 3ch61 Cellular Communication Network Factor 1 Cysteine-Rich Angiogenic Inducer 61 Insulin-Like Growth Factor-Binding Protein 10 Ibp-10 Igf-Binding Protein 10 Igfbp-10 Protein Cyr61 |
| Database Links | Reactome: R-MMU-381426 Reactome: -MMU-8957275 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Ccn Family Member 1 ELISA kit 3ch61 ELISA kit Cellular Communication Network Factor 1 ELISA kit Cysteine-Rich Angiogenic Inducer 61 ELISA kit Insulin-Like Growth Factor-Binding Protein 10 ELISA kit Ibp-10 ELISA kit Igf-Binding Protein 10 ELISA kit Igfbp-10 ELISA kit Protein Cyr61 ELISA kit Ccn1 ELISA kit Cyr61 ELISA kit Igfbp10 ELISA kit |
| output |
Information sourced from Uniprot.org
