| Short Description : | Recombinant-Mouse COL3A1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Supplied as a 0.22 Mu m filtered solution in 20mM HAc-NaAc, 150mM NaCl, pH 4.5. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | Col3a1 |
| Gene ID: | 12825 |
| Uniprot ID: | CO3A1_MOUSE |
| Immunogen: | Mus musculus (Mouse) |
| Immunogen Region: | Gln155-Gly1219 |
| Post Translational Modifications | Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group. |
| Function | Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. |
| Protein Name | Collagen Alpha-1(Iii Chain |
| Database Links | Reactome: R-MMU-1442490Reactome: -MMU-1474244Reactome: -MMU-1650814Reactome: -MMU-186797Reactome: -MMU-198933Reactome: -MMU-2022090Reactome: -MMU-216083Reactome: -MMU-3000171Reactome: -MMU-3000178Reactome: -MMU-419037Reactome: -MMU-8874081Reactome: -MMU-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Collagen Alpha-1(Iii Chain proteinCol3a1 protein |
Information sourced from Uniprot.org