Post Translational Modifications | Glycosylated. Phosphorylated on tyrosine residue in response to rhodocytin binding. |
Function | C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN. After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2. |
Protein Name | C-Type Lectin Domain Family 1 Member BC-Type Lectin-Like Receptor 2Clec-2 |
Database Links | Reactome: R-MMU-114604Reactome: -MMU-9707616 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Protein Names | C-Type Lectin Domain Family 1 Member B proteinC-Type Lectin-Like Receptor 2 proteinClec-2 proteinClec1b proteinClec2 protein |
Information sourced from Uniprot.org