Tissue Specificity | Weakly expressed in the liver and kidney. In reproductive organs expressed in connective tissues such as ligaments of the ovary and oviduct in females, and of testis, epididymis and certain male accessory sex glands in males. Expression was high in uterine myometrium. Weakly expressed in cartilage of the femoral head, patella, articular facets of vertebrae, in the annulus fibrosus of intervertebral disks. In normal cartilage, expression was confined to articular chondrocytes especially in the superficial zone. |
Post Translational Modifications | |
Function | Implicated in tumor angiogenesis. May inhibits BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. May play a role during myoblast and osteoblast differentiation, and maturation. |
Protein Name | Chordin-Like Protein 2 |
Database Links | |
Cellular Localisation | Secreted |
Alternative ELISA Names | Chordin-Like Protein 2 ELISA kitChrdl2 ELISA kitChl2 ELISA kit |
output | |
Information sourced from Uniprot.org