| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | |
| Function | ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis. |
| Protein Name | Chromodomain-Helicase-Dna-Binding Protein 4Chd-4Atp-Dependent Helicase Chd4Mi-2 Autoantigen 218 Kda ProteinMi2-Beta |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427389Reactome: R-HSA-6804758Reactome: R-HSA-73762Reactome: R-HSA-8943724Reactome: R-HSA-9031628Reactome: R-HSA-9679191Reactome: R-HSA-9843940Reactome: R-HSA-9844594Reactome: R-HSA-9845323 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeAssociates With Centrosomes In InterphaseLocalizes To Sites Of Dna Damage In A Manner Dependent On Zmynd8 And Znf687 |
| Alternative ELISA Names | Chromodomain-Helicase-Dna-Binding Protein 4 ELISA kitChd-4 ELISA kitAtp-Dependent Helicase Chd4 ELISA kitMi-2 Autoantigen 218 Kda Protein ELISA kitMi2-Beta ELISA kitCHD4 ELISA kit |
| output | |
Information sourced from Uniprot.org