| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse CDKN2A/p16INK4a-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | Cdkn2a |
| Gene ID: | 12578 |
| Uniprot ID: | CDN2A_MOUSE |
| Immunogen Region: | Met1-Ser135 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. |
| Protein Name | Cyclin-Dependent Kinase Inhibitor 2aCyclin-Dependent Kinase 4 Inhibitor ACdk4iP16-Ink4aP16-Ink4 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Cyclin-Dependent Kinase Inhibitor 2a proteinCyclin-Dependent Kinase 4 Inhibitor A proteinCdk4i proteinP16-Ink4a proteinP16-Ink4 proteinCdkn2a proteinP16ink4a protein |
Information sourced from Uniprot.org