Name: Mouse CD86/B7-2 protein (Recombinant-Active) (C-His) (STJP012854)
SKU: STJP012854-100
Price: 627.21 USD
Availability: InStock

Mouse CD86/B7-2 protein (Recombinant-Active) (C-His) (STJP012854)

SKU:

STJP012854-100

$627.21

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Short Description :	Recombinant-Active-Mouse CD86/B7-2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:	ELISA/WB
Host:	Mammalian Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation:	Unconjugated
Dilution Range:	Reconstitute in sterile water for a stock solution.
Formulation:	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Polyubiquitinated.which is promoted by MARCH8 and results in endocytosis and lysosomal degradation.
Function	Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.
Protein Name	T-Lymphocyte Activation Antigen Cd86 Activation B7-2 Antigen Early T-Cell Costimulatory Molecule 1 Etc-1 Cd Antigen Cd86
Database Links	Reactome: R-MMU-1257604 Reactome: -MMU-389356 Reactome: -MMU-389357 Reactome: -MMU-389359 Reactome: -MMU-389513 Reactome: -MMU-6811558
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	T-Lymphocyte Activation Antigen Cd86 protein Activation B7-2 Antigen protein Early T-Cell Costimulatory Molecule 1 protein Etc-1 protein Cd Antigen Cd86 protein Cd86 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP002739	Mouse B7-2/CD86 protein (Recombinant) (C-His) (STJP002739)	HEK293 cells
STJP011997	Human CD86/B7-2 protein (Recombinant-Active) (C-His) (STJP011997)	Mammalian Cells	ELISA/WB
STJP004708	Human CD86/B7-2 protein (Recombinant) (C-His) (STJP004708)	Mammalian Cells	ELISA/Immunogen/SDS-PAGE/WB
STJP002560	Human B7-2/CD86 protein (Recombinant) (C-His) (STJP002560)	HEK293 cells
STJP020268	Cynomolgus B7-2/CD86 protein (Recombinant) (C-His) (STJP020268)	HEK293 cells

Mouse CD86/B7-2 protein (Recombinant-Active) (C-His) (STJP012854)

General Information