Mouse CD83 (Cluster Of Differentiation 83) Sandwich ELISA Kit (STJE0007824)

SKU:
STJE0007824
£413.50 - £575.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 35pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description : This CD83 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Cd83
Gene ID: 12522
Uniprot ID: CD83_MOUSE
Sample Type: serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Abundantly expressed in spleen and brain, but is also detected in most tissues analyzed.
Post Translational Modifications
Function Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHC II trafficking MARCHF8. Also inhibits MARCHF1 association with MHC II and ubiquitination of MHCII. In addition, acts as an important modulator of protective responses against acute infections.
Protein Name Cd83 Antigen
Mcd83
Cd Antigen Cd83
Database Links
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Cd83 Antigen ELISA kit
Mcd83 ELISA kit
Cd Antigen Cd83 ELISA kit
Cd83 ELISA kit
output

Information sourced from Uniprot.org