| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse CD7-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: | The activity was tested by the ability of immobilized recombinant human SECTM1 to bind mouse CD7. NA |
| Gene Symbol: | Cd7 |
| Gene ID: | 12516 |
| Uniprot ID: | CD7_MOUSE |
| Immunogen Region: | ECD |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of Mouse CD7 including an C-terminal His tag was expressed in HEK293 cells. NA |
| Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of gamma-interferon levels. |
| Protein Name | T-Cell Antigen Cd7Cd Antigen Cd7 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | T-Cell Antigen Cd7 proteinCd Antigen Cd7 proteinCd7 protein |
Information sourced from Uniprot.org