Mouse CD68 protein (Recombinant) (N-His) (STJP009807)

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STJP009807
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse CD68-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Cd68
Gene ID: 12514
Uniprot ID: CD68_MOUSE
Immunogen Region: Gly125-Ser291
Immunogen: Mus musculus (Mouse)
Post Translational Modifications N- and O-glycosylated.
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Protein Name Macrosialin
Cd Antigen Cd68
Database Links Reactome: R-MMU-6798695
Cellular Localisation Isoform Long: Endosome Membrane
Single-Pass Type I Membrane Protein
Lysosome Membrane
Isoform Short: Cell Membrane
Alternative Protein Names Macrosialin protein
Cd Antigen Cd68 protein
Cd68 protein

Information sourced from Uniprot.org