| Short Description : | Recombinant-Mouse CD68-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | Cd68 |
| Gene ID: | 12514 |
| Uniprot ID: | CD68_MOUSE |
| Immunogen: | Mus musculus (Mouse) |
| Immunogen Region: | Gly125-Ser291 |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
| Protein Name | MacrosialinCd Antigen Cd68 |
| Database Links | Reactome: R-MMU-6798695 |
| Cellular Localisation | Isoform Long: Endosome MembraneSingle-Pass Type I Membrane ProteinLysosome MembraneIsoform Short: Cell Membrane |
| Alternative Protein Names | Macrosialin proteinCd Antigen Cd68 proteinCd68 protein |
Information sourced from Uniprot.org