Post Translational Modifications | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. |
Protein Name | Intercellular Adhesion Molecule 1Icam-1Mala-2Myd10Cd Antigen Cd54 |
Database Links | Reactome: R-MMU-198933Reactome: -MMU-216083 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Intercellular Adhesion Molecule 1 proteinIcam-1 proteinMala-2 proteinMyd10 proteinCd Antigen Cd54 proteinIcam1 proteinIcam-1 protein |
Information sourced from Uniprot.org