Mouse CD54/ICAM1 protein (Recombinant) (N-His) (STJP011033)

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STJP011033
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse CD54/ICAM1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Icam1
Gene ID: 15894
Uniprot ID: ICAM1_MOUSE
Immunogen Region: Leu120-Gln321
Immunogen: Mus musculus (Mouse)
Post Translational Modifications Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Protein Name Intercellular Adhesion Molecule 1
Icam-1
Mala-2
Myd10
Cd Antigen Cd54
Database Links Reactome: R-MMU-198933
Reactome: -MMU-216083
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Intercellular Adhesion Molecule 1 protein
Icam-1 protein
Mala-2 protein
Myd10 protein
Cd Antigen Cd54 protein
Icam1 protein
Icam-1 protein

Information sourced from Uniprot.org