Function | Synthesizes the second messengers cyclic ADP-ribose (cADPR) and nicotinate-adenine dinucleotide phosphate (NAADP), the former a second messenger for glucose-induced insulin secretion, the latter a Ca(2+) mobilizer. Also has cADPR hydrolase activity. |
Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 12'-Phospho-Adp-Ribosyl Cyclase2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase2'-Phospho-Cyclic-Adp-Ribose TransferaseAdp-Ribosyl Cyclase 1Adprc 1Cyclic Adp-Ribose Hydrolase 1Cadpr Hydrolase 1I-19Nim-R5 AntigenCd Antigen Cd38 |
Database Links | Reactome: R-MMU-196807 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Protein Names | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 protein2'-Phospho-Adp-Ribosyl Cyclase protein2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase protein2'-Phospho-Cyclic-Adp-Ribose Transferase proteinAdp-Ribosyl Cyclase 1 proteinAdprc 1 proteinCyclic Adp-Ribose Hydrolase 1 proteinCadpr Hydrolase 1 proteinI-19 proteinNim-R5 Antigen proteinCd Antigen Cd38 proteinCd38 protein |
Information sourced from Uniprot.org