Post Translational Modifications | Isoform 1: Not glycosylated. Isoform 4: N-glycosylated. |
Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
Protein Name | C-Type Lectin Domain Family 9 Member ADendritic Cell Natural Killer Lectin Group Receptor 1Cd Antigen Cd370 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Protein Names | C-Type Lectin Domain Family 9 Member A proteinDendritic Cell Natural Killer Lectin Group Receptor 1 proteinCd Antigen Cd370 proteinClec9a proteinDngr-1 protein |
Information sourced from Uniprot.org