Mouse CD33/Siglec-3 protein (Recombinant) (C-His) (STJP013865)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse CD33/Siglec-3-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | Cd33 |
| Gene ID | 12489 |
| Uniprot ID | CD33_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Asp18-Glu240 (Gly236R) |
Additional Info
| Post Translational Modifications | Glycosylated. Phosphorylation is involved in binding to PTPN6 and PTPN11. |
| Function | Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Preferentially binds sialic acid to the short O-linked glycans of certain mucins. |
| Protein Name | Myeloid Cell Surface Antigen Cd33Sialic Acid-Binding Ig-Like Lectin 3Siglec-3Cd Antigen Cd33 |
| Database Links | Reactome: R-MMU-198933Reactome: -MMU-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Myeloid Cell Surface Antigen Cd33 proteinSialic Acid-Binding Ig-Like Lectin 3 proteinSiglec-3 proteinCd Antigen Cd33 proteinCd33 proteinSiglec3 protein |
Information sourced from Uniprot.org