| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | Cdcp1 |
| Gene ID: | 109332 |
| Uniprot ID: | CDCP1_MOUSE |
| Immunogen: | Recombinant Mouse CD318 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Arg25-Ala667) of mouse CDCP1/CD318 (Accession #NP_598735.2) fused with a 6×His, Avi tag at the C-terminus. |
| Immunogen Region: | Arg25-Ala667 |
| Immunogen Sequence: | RGTEASEIALPQRSGVTVSI KLGNPALPVKICYIVMSRQH ITELIIRPGERKSFTFSCSN PEKHFVLKIEKNIDCMSGPC PFGEVHLQPSTSELPILNRT FIWDVRAHKSIGLELQFATP RLRQIGPGESCADGVTHSIS GHIDATEVRIGTFCSNGTVS RIKMQEGVKMALHLPWFHRR NVSGFSIANRSSIKRLCIIE SVFEGEGSATLMSANYPGGF PEDELMTWQFVVPAHLRAS |
| Function | May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis. |
| Protein Name | Cub Domain-Containing Protein 1Membrane Glycoprotein Gp140Transmembrane And Associated With Src KinasesCd Antigen Cd318 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinIts Shedding May Lead To A Soluble Peptide |
| Alternative Protein Names | Cub Domain-Containing Protein 1 proteinMembrane Glycoprotein Gp140 proteinTransmembrane And Associated With Src Kinases proteinCd Antigen Cd318 proteinCdcp1 protein |
Information sourced from Uniprot.org
