Function | Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB and stimulates the proliferation of T-cells. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production. |
Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 14Cd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form |
Database Links | Reactome: R-MMU-5668541Reactome: -MMU-5676594 |
Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinTumor Necrosis Factor Ligand Superfamily Member 14Soluble Form: Secreted |
Alternative Protein Names | Tumor Necrosis Factor Ligand Superfamily Member 14 proteinCd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form proteinTnfsf14 proteinLight protein |
Information sourced from Uniprot.org