Function | Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. |
Protein Name | Interleukin-13 Receptor Subunit Alpha-2Il-13 Receptor Subunit Alpha-2Il-13r Subunit Alpha-2Il-13r-Alpha-2Il-13ra2Cd Antigen Cd213a2 |
Database Links | Reactome: R-MMU-6785807 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
Alternative Protein Names | Interleukin-13 Receptor Subunit Alpha-2 proteinIl-13 Receptor Subunit Alpha-2 proteinIl-13r Subunit Alpha-2 proteinIl-13r-Alpha-2 proteinIl-13ra2 proteinCd Antigen Cd213a2 proteinIl13ra2 protein |
Information sourced from Uniprot.org