Name: Mouse CD123/IL3RA protein (Recombinant) (C-Fc) (STJP013892)
SKU: STJP013892-100
Price: 414.5 GBP
Availability: InStock

Mouse CD123/IL3RA protein (Recombinant) (C-Fc) (STJP013892)

SKU:

STJP013892-100

£414.50

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Host:	Mammalian Cells
Applications:	ELISA/WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Mouse CD123/IL3RA-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Dilution Range:	Reconstitute in sterile water for a stock solution.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	< 1 EU/µg as determined by LAL test.

Function	Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.
Protein Name	Interleukin-3 Receptor Subunit Alpha Il-3 Receptor Subunit Alpha Il-3r Subunit Alpha Il-3r-Alpha Il-3ra Interleukin-3 Receptor Class Ii Alpha Chain Cd Antigen Cd123
Database Links
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Expressed On The Cell Surface Isoform 2: Endomembrane System Mostly Distributed Inside The Cells Except In The Nuclei And Is Not Transported To The Cell Surface
Alternative Protein Names	Interleukin-3 Receptor Subunit Alpha protein Il-3 Receptor Subunit Alpha protein Il-3r Subunit Alpha protein Il-3r-Alpha protein Il-3ra protein Interleukin-3 Receptor Class Ii Alpha Chain protein Cd Antigen Cd123 protein Il3ra protein Sut-1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP013275	Human CD123/IL3RA protein (Recombinant) (C-Fc) (STJP013275)	Mammalian Cells	ELISA/WB
STJP013891	Mouse CD123/IL3RA protein (Recombinant) (C-8*His) (STJP013891)	Mammalian Cells	ELISA/WB
STJP004446	Human CD123/IL3RA protein (Recombinant) (C-His) (STJP004446)	Mammalian Cells
STJP009804	Mouse CD123/IL3RA protein (Recombinant) (N-His) (STJP009804)	E. coli
STJP012550	Biotinylated Human CD123/IL3RA protein (C-Fc-Avi) {Biotin} (STJP012550)	Mammalian Cells	ELISA/WB

Mouse CD123/IL3RA protein (Recombinant) (C-Fc) (STJP013892)

General Information