Mouse CD112 (PRR2) protein (Recombinant) (STJP000514)

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STJP000514
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse CD112 (PRR2)-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: 0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Gene Symbol: Nectin2
Gene ID: 19294
Uniprot ID: NECT2_MOUSE
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding extracellular domain of mouse nectin-2 (CD112) including a C-terminal 6His tag was expressed in HEK293 cells. NA
Tissue Specificity Brain, spinal cord, spleen, kidney, heart and liver.
Function Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.
Protein Name Nectin-2
Herpes Virus Entry Mediator B
Herpesvirus Entry Mediator B
Hveb
Murine Herpes Virus Entry Protein B
Mhveb
Nectin Cell Adhesion Molecule 2
Poliovirus Receptor Homolog
Poliovirus Receptor-Related Protein 2
Cd Antigen Cd112
Database Links Reactome: R-MMU-198933
Reactome: -MMU-418990
Reactome: -MMU-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Nectin-2 protein
Herpes Virus Entry Mediator B protein
Herpesvirus Entry Mediator B protein
Hveb protein
Murine Herpes Virus Entry Protein B protein
Mhveb protein
Nectin Cell Adhesion Molecule 2 protein
Poliovirus Receptor Homolog protein
Poliovirus Receptor-Related Protein 2 protein
Cd Antigen Cd112 protein
Nectin2 protein
Mph protein
Pvr protein
Pvrl2 protein
Pvs protein

Information sourced from Uniprot.org

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