Mouse CD112/Nectin-2/PVRL2 protein (Recombinant) (C-His) (STJP013988)

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STJP013988-100
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Short Description :Recombinant-Mouse CD112/Nectin-2/PVRL2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:Nectin2
Gene ID:19294
Uniprot ID:NECT2_MOUSE
Immunogen:Mus musculus (Mouse)
Immunogen Region:Gln32-Gly351
Function Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.
Protein Name Nectin-2
Herpes Virus Entry Mediator B
Herpesvirus Entry Mediator B
Hveb
Murine Herpes Virus Entry Protein B
Mhveb
Nectin Cell Adhesion Molecule 2
Poliovirus Receptor Homolog
Poliovirus Receptor-Related Protein 2
Cd Antigen Cd112
Database Links Reactome: R-MMU-198933
Reactome: -MMU-418990
Reactome: -MMU-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Nectin-2 protein
Herpes Virus Entry Mediator B protein
Herpesvirus Entry Mediator B protein
Hveb protein
Murine Herpes Virus Entry Protein B protein
Mhveb protein
Nectin Cell Adhesion Molecule 2 protein
Poliovirus Receptor Homolog protein
Poliovirus Receptor-Related Protein 2 protein
Cd Antigen Cd112 protein
Nectin2 protein
Mph protein
Pvr protein
Pvrl2 protein
Pvs protein

Information sourced from Uniprot.org

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