| Host: | E.coli |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse CCL3/MIP-1-alpha-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, 1mM EDTA, pH 8.0. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | Ccl3 |
| Gene ID: | 20302 |
| Uniprot ID: | CCL3_MOUSE |
| Immunogen Region: | Ala24-Ala92 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3Heparin-Binding Chemotaxis ProteinL2g25bMacrophage Inflammatory Protein 1-AlphaMip-1-AlphaSis-AlphaSmall-Inducible Cytokine A3Ty-5 |
| Database Links | Reactome: R-MMU-380108 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 3 proteinHeparin-Binding Chemotaxis Protein proteinL2g25b proteinMacrophage Inflammatory Protein 1-Alpha proteinMip-1-Alpha proteinSis-Alpha proteinSmall-Inducible Cytokine A3 proteinTy-5 proteinCcl3 proteinMip1a proteinScya3 protein |
Information sourced from Uniprot.org
