Mouse CCL3/MIP-1 alpha protein (Recombinant) (His-Tag) (STJP017873)
SPECIFICATIONS
HostE.coli
ImmunogenMouse
General Information
| Short Description | Recombinant-Mouse CCL3/MIP-1 alpha-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Sodium citrate buffer (pH 3.5) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Ccl3 |
| Gene ID | 20302 |
| Uniprot ID | CCL3_MOUSE |
| Accession Number | NP_035467 |
| Immunogen | Mouse |
| Immunogen Region | 24-92aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAPYGAD TPTACCFSYS RKIPRQFIVD YFETSSLCSQ PGVIFLTKRN RQICADSKET WVQEYITDLE LNA |
Additional Info
| Tissue Specificity | Expressed in lung, spleen, and pancreas. |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3Heparin-Binding Chemotaxis ProteinL2g25bMacrophage Inflammatory Protein 1-AlphaMip-1-AlphaSis-AlphaSmall-Inducible Cytokine A3Ty-5 |
| Database Links | Reactome: R-MMU-380108 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 3 proteinHeparin-Binding Chemotaxis Protein proteinL2g25b proteinMacrophage Inflammatory Protein 1-Alpha proteinMip-1-Alpha proteinSis-Alpha proteinSmall-Inducible Cytokine A3 proteinTy-5 proteinCcl3 proteinMip1a proteinScya3 protein |
Information sourced from Uniprot.org