Mouse CCL3/MIP-1 alpha protein (Recombinant) (His-Tag) (STJP017873)

SPECIFICATIONS
HostE.coli
ImmunogenMouse
STJP017873
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General Information

Short DescriptionRecombinant-Mouse CCL3/MIP-1 alpha-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Sodium citrate buffer (pH 3.5) containing 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCcl3
Gene ID20302
Uniprot IDCCL3_MOUSE
Accession NumberNP_035467
ImmunogenMouse
Immunogen Region24-92aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MGSMAPYGAD TPTACCFSYS RKIPRQFIVD YFETSSLCSQ PGVIFLTKRN RQICADSKET WVQEYITDLE LNA

Additional Info

Tissue Specificity Expressed in lung, spleen, and pancreas.
Function Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Protein Name C-C Motif Chemokine 3
Heparin-Binding Chemotaxis Protein
L2g25b
Macrophage Inflammatory Protein 1-Alpha
Mip-1-Alpha
Sis-Alpha
Small-Inducible Cytokine A3
Ty-5
Database Links Reactome: R-MMU-380108
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 3 protein
Heparin-Binding Chemotaxis Protein protein
L2g25b protein
Macrophage Inflammatory Protein 1-Alpha protein
Mip-1-Alpha protein
Sis-Alpha protein
Small-Inducible Cytokine A3 protein
Ty-5 protein
Ccl3 protein
Mip1a protein
Scya3 protein

Information sourced from Uniprot.org

Citations

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