| Tissue Specificity | Isoform 2 is the major form in all tissues examined. Isoform 1 accounts for 5-10% in tissues such as skeletal muscle, liver and brain, and 30% in myoblasts. Isoforms 4 and 5 are testis-specific. Isoform 6 is highly expressed in heart and skeletal muscle with lower levels in liver, brain and testis. Isoform 7 is expressed at high levels in liver. |
| Post Translational Modifications | |
| Function | Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. |
| Protein Name | CalpastatinCalpain Inhibitor |
| Database Links | Reactome: R-MMU-1474228 |
| Cellular Localisation | |
| Alternative ELISA Names | Calpastatin ELISA kitCalpain Inhibitor ELISA kitCast ELISA kit |
| output | |
Information sourced from Uniprot.org