| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse C4B-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | C4b |
| Gene ID: | 12268 |
| Uniprot ID: | CO4B_MOUSE |
| Immunogen Region: | Glu988-Thr1317 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. Catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. |
| Protein Name | Complement C4-B Cleaved Into - Complement C4 Beta Chain - Complement C4 Alpha Chain - C4a Anaphylatoxin - Complement C4 Gamma Chain |
| Database Links | Reactome: R-MMU-166663Reactome: -MMU-174577Reactome: -MMU-381426Reactome: -MMU-8957275Reactome: -MMU-977606 |
| Cellular Localisation | SecretedSynapseCell ProjectionAxonDendrite |
| Alternative Protein Names | Complement C4-B Cleaved Into - Complement C4 Beta Chain - Complement C4 Alpha Chain - C4a Anaphylatoxin - Complement C4 Gamma Chain proteinC4b proteinC4 protein |
Information sourced from Uniprot.org