| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse C1QA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | C1qa |
| Gene ID: | 12259 |
| Uniprot ID: | C1QA_MOUSE |
| Immunogen Region: | Asp111-Ala245 |
| Immunogen: | Mus musculus (Mouse) |
| Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
| Protein Name | Complement C1q Subcomponent Subunit A |
| Database Links | Reactome: R-MMU-166663Reactome: -MMU-173623Reactome: -MMU-977606 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Complement C1q Subcomponent Subunit A proteinC1qa protein |
Information sourced from Uniprot.org