Mouse BMP1 protein (Recombinant) (N-GST) (STJP004059)

SKU:
STJP004059
$443.48 - $1,940.63
Free Shipping
Processing The item has been added

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse BMP1-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Bmp1
Gene ID: 12153
Uniprot ID: BMP1_MOUSE
Immunogen Region: Glu615-Ser848
Immunogen: Mus musculus (Mouse)
Function Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation.
Protein Name Bone Morphogenetic Protein 1
Bmp-1
Mammalian Tolloid Protein
Mtld
Procollagen C-Proteinase
Pcp
Database Links Reactome: R-MMU-1650814
Reactome: -MMU-2214320
Reactome: -MMU-2243919
Reactome: -MMU-8963896
Cellular Localisation Golgi Apparatus
Trans-Golgi Network
Secreted
Extracellular Space
Extracellular Matrix
Co-Localizes With Postn In The Golgi
Alternative Protein Names Bone Morphogenetic Protein 1 protein
Bmp-1 protein
Mammalian Tolloid Protein protein
Mtld protein
Procollagen C-Proteinase protein
Pcp protein
Bmp1 protein

Information sourced from Uniprot.org