Post Translational Modifications | Phosphorylated on a cytoplasmic Ser residue. |
Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
Protein Name | Asialoglycoprotein Receptor 1Asgp-R 1Asgpr 1Hepatic Lectin 1Hl-1Mhl-1 |
Database Links | Reactome: R-MMU-446203 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Protein Names | Asialoglycoprotein Receptor 1 proteinAsgp-R 1 proteinAsgpr 1 proteinHepatic Lectin 1 proteinHl-1 proteinMhl-1 proteinAsgr1 proteinAsgr-1 protein |
Information sourced from Uniprot.org