Mouse ANG2 (Angiopoietin-2) Antibody Pair (STJAP00563)
General Information
| Short Description | This ANG2 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Sheep/Sheep |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | Angpt2 |
| Gene ID | 11601 |
| Uniprot ID | ANGP2_MOUSE |
| Immunogen | Capture immunogen: Recombinant Mouse ANG2 protien.Detection Immunogen: Recombinant Mouse ANG2 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Function | Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Involved in the regulation of lymphangiogenesis. |
| Protein Name | Angiopoietin-2Ang-2 |
| Database Links | Reactome: R-MMU-210993 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Angiopoietin-2 antibody pairAng-2 antibody pairAngpt2 antibody pairAgpt2 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Mouse ANG2 (Angiopoietin-2) Antibody Pair (STJAP00563)
This antibody pair is validated to detect mouse Angiopoietin-2 (ANG2), corresponding to UniProt accession O35608. It is intended for use with mouse-derived samples and has not been validated for reactivity in other species.
The capture antibody is supplied unconjugated, while the detection antibody is biotin-conjugated. Both are sheep-derived, purified by antigen affinity, and supplied at 0.5 mg/mL.
This pair has been validated for use in ELISA. No other assay formats are listed in the product specifications.
The product has been evaluated with serum, plasma, and other biological fluids of mouse origin. Suitability for additional sample types has not been specified.
The capture antibody is formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5, while the detection antibody is formulated in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5. Both components should be stored at -20°C for long-term storage, and freeze-thaw cycles should be avoided.
Both the capture and detection antibodies were raised against recombinant mouse ANG2 protein and are purified by antigen affinity. Both antibodies are sheep-derived polyclonal reagents.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.